The device may be hand-held or clamped to a stand. The device is lowered into the sample or mixture and the motor activated. A rotor-stator processes a single sample at a time high-throughput and continuous use models are available.Īn immersion blender has an electric motor that powers rotating blades at the end of a shaft. Samples are subjected to tearing, shear fluid forces, and cavitation (bubble formation and collapse). Depending on the equipment, many samples can be processed simultaneously with this method.Īnother mechanical homogenization method is the rotor-stator these devices have a fast-spinning inner rotor and a stationary outer sheath (stator). The sample is added to a vial that contains these small particles the tubes are then rapidly agitated, which breaks down the materials. Some substances can be mechanically homogenized using beads and other small pieces of metal or minerals. Sonic dismembrators can break up cells and fragment DNA molecules by subjecting the sample to ultrasonic waves that create small fragments. These include bead mills, sonication, rotor-stator mechanical, high pressure, and other physical methods.įor biological work, sonication may adequately disrupt or deactivate biological material via the process of sonoporation. Different methods have been developed for disrupting cell walls and other structures. Homogenization is a common sample preparation step for analyzing nucleic acids, proteins, cells, metabolism, pathogens, and other targets.Ĭell fractionation releases the contents of cells, and newer methods have been designed to consider quality and environmental aspects, cross-contamination, aerosol generations, infection risk, and noise levels. Homogenizers can be used with tissue, plant, food, soil, and other sample types. Includes accessories such as generator probes of varying tips, stand assemblies, bead mill tubes, and more. Devices designed for overhead immersion into substances ideal for pulverization of plant/animal tissue, grain/seed, sample prep, and more.
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